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Biorank Laboratories
General Longevity & Healthspan
Educational purposes only. Not medical advice. Always consult your doctor before starting supplements.
Evidence-based supplement protocol for extending healthspan and slowing biological aging across multiple hallmarks of aging
Alysa Analysis for
General Longevity & Healthspan
Priority Guide
Direct NAD+ precursor that restores age-related NAD+ decline. NAD+ is required for SIRT1-mediated DNA repair, mitochondrial function, and epigenetic maintenance. Human RCTs show improved muscle insulin sensitivity and aerobic capacity in older adults.
Recommended Dose
500mg daily (sublingual or enteric-coated on empty stomach)
Expected Timeframe
4-12 weeks for biomarker changes
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Slows telomere shortening — the most direct measure of cellular aging. JAMA study showed highest-quartile omega-3 levels associated with slowest telomere attrition. Also reduces chronic low-grade inflammation (inflammaging), the driver of most age-related diseases.
Recommended Dose
2g combined EPA/DHA daily
Expected Timeframe
8-12 weeks
Regulates over 1,000 genes including those involved in immune surveillance, DNA repair, and apoptosis. Deficiency accelerates biological aging. Large cohort studies (UK Biobank) link optimal levels (40-60 ng/mL) to reduced all-cause mortality.
Recommended Dose
5000 IU daily (test 25-OH-D levels)
Expected Timeframe
3-6 months to reach optimal levels
Cofactor in 600+ enzymatic reactions including DNA repair, protein synthesis, and energy metabolism. Most adults are deficient. Threonate form crosses the blood-brain barrier for neuroprotective effects.
Recommended Dose
400mg elemental magnesium daily
Expected Timeframe
2-4 weeks
Maintains phosphocreatine energy buffer in brain and muscle — both decline with age. RCTs show cognitive benefits in older adults, preservation of lean mass, and improved bone density. One of the most extensively studied supplements in existence.
Recommended Dose
5g daily (no loading needed)
Expected Timeframe
4-8 weeks
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3 of 5 supplements available in our database — add them all at once.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
Always consult your doctor or qualified healthcare provider before starting any supplement regimen, especially if you have existing health conditions or take medications.
Supplements may interact with medications and are not intended to diagnose, treat, cure, or prevent any disease.
The evidence ratings reflect our analysis of published research and may not capture every nuance of individual health situations.