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RankingsNootropics
Nootropics
Cognitive enhancement supplements. Separating real nootropic science from Silicon Valley hype.
18 products rankedTop score: 64
#1
Nootropics DepotNootropics
Alpha-GPC 300mg
Alpha-GPC is the most bioavailable choline source for the brain, used to support acetylcholine production — a neurotransmitter critical for memory and learning. Nootropics Depot is a well-respected specialty brand with rigorous third-party testing. At 300mg per capsule, dosing is flexible for both cognitive support and exercise performance protocols.
Solid Choice$22.00
$0.37/doseTrue cost: $1.11/dose
74
#2
Jarrow FormulasNootropics
SAMe 400mg
S-Adenosyl-L-Methionine at the clinically studied 400mg dose. Jarrow uses enteric-coated tablets to protect the notoriously unstable SAMe molecule from stomach acid degradation. Strong clinical evidence for depression and osteoarthritis, but comes with real safety considerations including potential for triggering mania in bipolar patients.
Worth Buying$35.00
$0.58/dose
73
#3
NOW FoodsNootropics
Phosphatidylserine 100mg
Phosphatidylserine (PS) is a phospholipid critical for cell membrane integrity in the brain. NOW Foods provides 100mg per softgel from soy-derived sources. PS has one of the few FDA-qualified health claims for cognitive function, though the claim is heavily caveated with 'very limited and preliminary' language.
Solid Choice$22.00
$0.37/dose
71
#4
Double Wood SupplementsNootropics
Lion's Mane Mushroom 1000mg
Lion's Mane (Hericium erinaceus) is a medicinal mushroom with preliminary evidence for nerve growth factor stimulation. Double Wood offers 1000mg per serving at a reasonable price. The science is genuinely promising for neuroprotection, but the hype has outpaced the human clinical evidence — most studies are in vitro or in animal models.
Solid Choice$20.00
$0.33/dose
Hype penalty: -2 pts
68
#5
OnnitNootropics
Alpha Brain
One of the original nootropic stacks, backed by two small company-funded studies. Proprietary blends hide doses of everything interesting. The Joe Rogan premium is real.
Overhyped$79.99
$1.78/doseTrue cost: $5.34/dose
Hype penalty: -12 pts
52
#6
Gorilla MindNootropics
Turkesterone
The supplement industry's latest 'natural anabolic' hype cycle. Turkesterone has almost no human evidence. Animal studies used different forms at massive doses. Save your money.
Evidence Weak$49.99
$1.67/doseTrue cost: $5.01/dose
Hype penalty: -15 pts
42