Quercetin 500mg

Name: NOW Foods Quercetin 500mg
Brand: NOW Foods
Price: 18.00 USD
Availability: InStock

Quercetin is a widely available flavonoid with anti-inflammatory, antioxidant, and emerging senolytic properties. NOW Foods delivers 500mg at an exceptional price ($0.15/serving). While quercetin alone is a weaker senolytic than dasatinib+quercetin combinations used in research, it has broader evidence for anti-inflammatory effects, immune support, and cardiovascular health.

73/ 100

Biorank Score

Independently ranked

73/ 100

Biorank Score

Independently ranked by Biorank Laboratories

Our Verdict

Worth Buying

NOW Foods Quercetin scores 73 — well above most longevity supplements — because quercetin has a broader evidence base than just the senolytic narrative. The anti-inflammatory, cardiovascular, and immune support evidence is solid from multiple independent research groups. The value score (85) is the highest in the longevity category at just $0.15/serving. NOW Foods is a well-established brand. No hype penalty because quercetin is not a trendy longevity molecule — it is a well-studied flavonoid with legitimate health applications.

Key Findings

Broader evidence base than most longevity supplements — anti-inflammatory, cardiovascular, and immune support
Justice et al. (2019) showed D+Q senolytic effects in humans, but quercetin alone is a weak senolytic
Li et al. (2016) meta-analysis showed quercetin reduced C-reactive protein (inflammation marker)
Exceptional value at $0.15/serving — the most affordable product in the longevity category
Decades of safety data as a dietary flavonoid supplement

Evidence Analysis

Quercetin has a broader evidence base than most longevity supplements. Zhu et al. (2015, Aging Cell) showed dasatinib + quercetin (D+Q) was a potent senolytic combination in mice. Justice et al. (2019, EBioMedicine) published the first human D+Q senolytic trial in idiopathic pulmonary fibrosis patients, showing reduced senescent cell markers after 3 weeks. However, quercetin alone is a much weaker senolytic than the D+Q combination. Independent of senolytic effects, quercetin has evidence for anti-inflammatory activity: Li et al. (2016, Nutrients) meta-analysis showed quercetin reduced C-reactive protein. Heinz et al. (2010, European Journal of Clinical Nutrition) found quercetin reduced blood pressure in overweight subjects. Quercetin has been used as a dietary supplement for decades with an excellent safety profile.

Ingredient Breakdown

Ingredient	Dose	Effective Dose	Adequacy	Verdict
Quercetin Dihydrate	500mg	500-1000mg		Optimal

True Cost Analysis

Properly Dosed -- What You Pay Is What You Get

Listed Price

$0.15/serving

$4.50/month at 1 serving/day

True Cost Per Effective Dose

$0.15/effective dose

$4.50/month for effective dosing

Value Score

Excellent value

Where It Falls Short

Quercetin alone is a weak senolytic — the exciting senolytic research uses dasatinib + quercetin (D+Q), and dasatinib is a prescription cancer drug not available as a supplement. Oral bioavailability of quercetin is moderate (estimated 5-20%) and varies with formulation. NOW Foods does not use an enhanced bioavailability form (phytosome or liposomal). The anti-inflammatory effects are real but modest compared to pharmaceutical anti-inflammatories. Some quercetin supplements can interact with certain antibiotics and blood thinners.

Best For

Budget-conscious consumers who want a well-evidenced anti-inflammatory supplement ($0.15/serving)
Those seeking broad-spectrum flavonoid benefits (anti-inflammatory, cardiovascular, immune)
People interested in senolytic science who want an affordable entry point
Adults looking for natural anti-inflammatory support with decades of safety data

Not Ideal For

Anyone expecting strong senolytic effects from quercetin alone (D+Q research requires prescription dasatinib)
Those who want enhanced bioavailability (NOW Foods uses standard quercetin, not phytosome form)
People on blood thinners or certain antibiotics (potential interactions)
Longevity enthusiasts seeking cutting-edge interventions (quercetin is well-established, not novel)